BIOCRYST PHARMACEUTICALS INC

Our Business We are a global biotechnology company focused on developing and commercializing medicines for hereditary angioedema ( HAE ) and other rare diseases, driven by our deep commitment to improving the lives of people living with these conditions. We have built a robust commercial infrastructure to support the successful commercialization of ORLADEYO, an oral, once-daily therapy discovered and developed internally for the prevention of HAE attacks. Our business strategy includes leveraging this established commercial platform to successfully commercialize a pipeline of potential first-in-class or best-in class oral small molecule and injectable protein therapeutics targeting a range of rare diseases. These programs are being pursued through both internal discovery efforts and strategic business development. By utilizing our existing commercial capabilities and focusing on rare disease markets, we believe that we can more effectively optimize costs and strategically allocate resources to support long-term, sustainable growth. Molecules from our discovery and business development efforts that are commercially available or that are in active development are summarized in the table below and are discussed in further detail under Products and Product Candidates in this Part I Item 1 Business section of this report. For a description of our relationships with third parties regarding our products and product candidates, see Business Collaborations, License and Other Relationships .