MIMEDX GROUP, INC.

A. Risk Factors beginning on page 21 below. Risks Related to Our Business and Industry If we do not successfully execute our priorities, our business, operating results and financial condition could be adversely affected. We are in a highly competitive and evolving field and face competition from well-established tissue processors and medical device manufacturers, as well as new market entrants. Our revenues depend on adequate reimbursement from public and private insurers and health systems and changes to the way in which our products are reimbursed in various sites of service could adversely impact our financial results. Rapid technological change could cause our products to become obsolete. Many of our products depend on the availability of tissue from human donors, and any disruption in supply could adversely affect our business. We depend on our senior leadership team and key employees and may not be able to retain or replace these employees or recruit additional qualified personnel. Our revenue, results of operations and cash flows may suffer upon the loss of a Group Purchasing Organization or Integrated Delivery Network. We contract with and are dependent on independent sales agents and distributors. Disruption of our processing facilities could adversely affect our business, financial condition and results of operations. To be commercially successful, we must educate physicians, where appropriate, how and when our products are proper alternatives to existing treatments and that our products should be used in their procedures.